Matthew R Smith Selected Research

Toremifene (Fareston)

1/2013	Toremifene to reduce fracture risk in men receiving androgen deprivation therapy for prostate cancer.
12/2011	Toremifene decreases vertebral fractures in men younger than 80 years receiving androgen deprivation therapy for prostate cancer.
9/2011	Emerging therapies to prevent skeletal morbidity in men with prostate cancer.
10/2010	Toremifene to reduce fracture risk in men receiving androgen deprivation therapy for prostate cancer.
4/2008	Toremifene improves lipid profiles in men receiving androgen-deprivation therapy for prostate cancer: interim analysis of a multicenter phase III study.
10/2006	Treatment-related osteoporosis in men with prostate cancer.
3/2006	Toremifene--a promising therapy for the prevention of prostate cancer and complications of androgen deprivation therapy.
12/2005	Therapy Insight: osteoporosis during hormone therapy for prostate cancer.
1/2005	Selective estrogen receptor modulators to prevent treatment-related osteoporosis.
1/2002	A phase II trial of interferon-alpha and toremifene in advanced renal cell cancer patients.

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Matthew R Smith Research Topics

Disease

175	Prostatic Neoplasms (Prostate Cancer) 07/2022 - 01/2002
61	Neoplasm Metastasis (Metastasis) 02/2022 - 02/2002
36	Neoplasms (Cancer) 07/2022 - 01/2002
22	Osteoporosis 11/2019 - 01/2002
18	Cardiovascular Diseases (Cardiovascular Disease) 07/2013 - 11/2004
16	Pain (Aches) 07/2022 - 12/2003
16	Insulin Resistance 04/2014 - 11/2004
13	Disease Progression 10/2018 - 12/2003
10	Obesity 01/2017 - 11/2004
9	Fatigue 01/2022 - 07/2004
9	Breast Neoplasms (Breast Cancer) 01/2020 - 01/2005
8	Myocardial Infarction 07/2013 - 09/2006
7	Bone Diseases (Bone Disease) 07/2012 - 01/2005
7	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2011 - 05/2004
7	Carcinoma (Carcinomatosis) 03/2006 - 11/2002
6	Coronary Disease (Coronary Heart Disease) 02/2016 - 09/2006
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 05/2015 - 06/2007
6	Flushing 01/2013 - 07/2004
6	Bone Resorption 01/2012 - 05/2003
5	Bone Fractures (Bone Fracture) 07/2022 - 07/2008
5	Anemia 01/2018 - 07/2008
5	Circulating Neoplastic Cells 01/2018 - 03/2010
4	Hypertension (High Blood Pressure) 01/2019 - 01/2009
4	Diabetes Mellitus 01/2009 - 11/2004
3	Exanthema (Rash) 01/2021 - 04/2018
3	Heart Diseases (Heart Disease) 11/2015 - 12/2010
3	Gynecomastia 05/2015 - 05/2009
3	Spontaneous Fractures (Pathological Fracture) 11/2012 - 12/2003
3	Metabolic Bone Diseases (Osteopenia) 07/2012 - 10/2009
3	Lung Neoplasms (Lung Cancer) 05/2009 - 01/2005
3	Renal Cell Carcinoma (Grawitz Tumor) 01/2005 - 01/2002
2	Inflammation (Inflammations) 12/2019 - 01/2012
2	Osteoporotic Fractures 11/2019 - 09/2011
2	Overweight 01/2017 - 01/2007
2	Cancer Pain 10/2015 - 01/2013

Drug/Important Bio-Agent (IBA)

105	AndrogensIBA 02/2022 - 01/2002
32	Prostate-Specific Antigen (Semenogelase)IBA 02/2022 - 07/2003
30	Gonadotropin-Releasing Hormone (GnRH)FDA Link 03/2014 - 02/2002
26	Hormones (Hormone)IBA 07/2022 - 01/2003
25	Zoledronic Acid (Zometa)FDA Link 12/2016 - 06/2003
23	Diphosphonates (Bisphosphonates)IBA 11/2019 - 01/2003
18	Denosumab FDA Link 11/2019 - 12/2005
16	Biomarkers (Surrogate Marker)IBA 07/2021 - 01/2003
15	Abiraterone AcetateIBA 01/2017 - 03/2010
10	apalutamideIBA 02/2022 - 12/2016
10	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 03/2010
10	Pharmaceutical PreparationsIBA 01/2020 - 12/2010
10	Toremifene (Fareston)FDA Link 01/2013 - 01/2002
9	Prednisone (Sone)FDA LinkGeneric 01/2020 - 03/2010
9	LipidsIBA 12/2019 - 04/2008
8	darolutamideIBA 07/2022 - 10/2018
8	Docetaxel (Taxotere)FDA Link 01/2022 - 01/2005
8	cabozantinibIBA 01/2020 - 01/2013
8	Triglycerides (Triacylglycerol)IBA 03/2014 - 02/2008
7	Leuprolide (Lupron)FDA LinkGeneric 12/2010 - 02/2002
6	Testosterone (Sustanon)FDA Link 01/2018 - 07/2003
6	abirateroneIBA 01/2018 - 01/2013
6	Pamidronate (Aredia)FDA LinkGeneric 08/2009 - 06/2003
5	Monoclonal AntibodiesIBA 10/2013 - 08/2009
5	HDL CholesterolIBA 01/2013 - 06/2007
5	collagen type I trimeric cross-linked peptideIBA 12/2011 - 06/2006
5	bicalutamide (Casodex)FDA LinkGeneric 02/2008 - 01/2003
4	Alkaline PhosphataseIBA 01/2020 - 12/2003
4	Tyrosine Kinase InhibitorsIBA 01/2020 - 11/2012
4	Androgen Receptor AntagonistsIBA 10/2019 - 12/2016
4	enzalutamideIBA 01/2018 - 05/2014
4	Selective Estrogen Receptor Modulators (SERM)IBA 05/2015 - 01/2005
4	Narcotics (Narcotic Analgesics)IBA 02/2015 - 11/2012
4	Analgesics (Analgesic Drugs)IBA 10/2014 - 12/2003
4	RANK LigandIBA 10/2013 - 08/2009
4	MineralsIBA 01/2013 - 10/2010
4	Collagen Type I (Type I Collagen)IBA 07/2012 - 03/2007
4	Estrogens (Estrogen)FDA Link 01/2012 - 01/2002
4	Goserelin (Zoladex)FDA Link 01/2009 - 12/2007
3	MicronutrientsIBA 01/2018 - 11/2015
3	LDL CholesterolIBA 01/2013 - 04/2008
3	Aromatase InhibitorsIBA 01/2012 - 11/2002
3	CholesterolIBA 02/2010 - 04/2008
3	Therapeutic UsesIBA 10/2006 - 01/2005
3	Biological ProductsIBA 06/2006 - 10/2004
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 10/2019
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2019
2	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 05/2015
2	Hemoglobins (Hemoglobin)IBA 01/2020 - 08/2007
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2020 - 08/2007
2	LigandsIBA 12/2019 - 03/2010
2	Radium-223IBA 01/2018 - 11/2015
2	RNA (Ribonucleic Acid)IBA 01/2018 - 03/2010
2	Opiate AlkaloidsIBA 10/2015 - 01/2013

Therapy/Procedure

131	Therapeutics 07/2022 - 01/2002
62	Castration 07/2022 - 07/2003
20	Drug Therapy (Chemotherapy) 01/2019 - 01/2005
11	Radiotherapy 01/2017 - 12/2003
8	Prostatectomy (Retropubic Prostatectomy) 01/2017 - 10/2004
7	Orchiectomy (Orchidectomy) 03/2014 - 04/2004
4	Drug Tapering 11/2015 - 01/2013
3	Duration of Therapy 01/2016 - 11/2005
2	Salvage Therapy 01/2017 - 12/2016
2	Aftercare (After-Treatment) 01/2017 - 01/2017
2	Life Support Care 10/2015 - 11/2014